RAE.

Artículo 3.
Titulo	Lewy and his inclusión bodies
Autores	Eliasz Engelhardt , Marleide da Mota Gomes
Campo de conocimiento	medicine- neuropsychology
Base de datos	REDALYC https://www.redalyc.org/articulo.oa?id=339551660012
Resumen	Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological, signature of the Lewy body diseases. In 1912, he published his seminal study, followed soon after by an update paper, and 10 years later, in 1923, by his voluminous book, where he exhaustively described the subject. The publication. provided extensive information on the pathology of Paralysis agitans, and the entirely novel finding of eosinophilic, inclusion bodies, which would become widely recognized and debated in the future. His discovery was acknowledged, by important researchers who even named the structure after him. However, after his last publication on the issue,,inexplicably, he never mentioned his histopathological discovery again. Despite several hypotheses, the reasons that led,him to neglect (reject) the structure which he so preeminently described have remained elusive.
Objetivo	Recognize a researcher who found an association and gave a final diagnosis to Parkinson's, because although the disease was already known but it was called (trembling palsy).
Conceptos principales	He was the first to recognize Parkinson's disease and associate it with Lewy bodies. He carried out a study where he revealed everything that Lewy bodies imply and how they are associated with Parkinson's.
Metodología	Mixed (Descriptive Study)
Instrumentos	Databases of people who were previously interested in investigating Lewy bodies and their relationship to Parkinson's.
Resultados	The investigation leads to the writing of two books in relation to the pathology of paralysis trembling, but the author did not talk about it again, although it was a great discovery for the investigation.
Conclusiones	Lewy described the pathology of Paralysis agitans, identifying a novel structure - eosinophilic inclusion bodies in neurons of some brain nuclei. After his 1912 seminal paper, and another that followed shortly after, he prepared and published, 10 years later, a massive book on the subject. After this, he never returned to the theme, nor mentioned his original finding. Despite several hypotheses, the reasons that led him to neglect (reject) the structure he so preeminently described, appear set to remain unsolved.
Referencia bibliográfica	Engelhardt, E., & da Mota Gomes, M. (2017). Lewy and his inclusion bodies. Discovery and rejection. Dementia & Neuropsychologia, 11(2), 198-201.
Autores RAE	Ingrid virguez Mejía.Mileydy Almonacid, Tatiana Ramirez.
Fecha	03/03/2023